Right off the top of my head [& I'm not a foley artist, so you'd have to work out the details]
sharp points to feet - high transients
lots of legs - 'skittering'
rhythmic walk - pattern that could become 'signature'...
& don't forget ...big, so lots of things dropped an octave, added subs
'skin' movement noises, not synced to ...
+Easier to design
+Infinite replication (in software)
+Often easier and faster to use
+More bandwidth/channels in a smaller form factor
+Better S/N performance in hardware
+Does stuff that cannot be (at least reasonably or cheaply, or at all) done with analog electronics
+Usually implements visual feedback of the ...
I know this all too well, though more in a general mixing context:
In a mix with certain qualities (but also problems that has to be fixed), it feels like no matter what you tweak to get around the issue, it influences the part you like too.
It may not directly translate to descisions on wether to use a given sample or not, but I think it has a lot in ...
I rely on a lot of digital tools when making sound. For instance, I often put an EQ on every channel, have a lot reverbs running and some compressors too. All automated, so I can get the most out of them (to my abilities) all of the time. I run a large number of tracks and busses. And I must say the noise reduction technology of today is way better than it ...