Specifically, the sound of an animal/deranged human/creature of some sort skittering and clattering around on a stone floor?
My application is for a large weighty creature, but your answers can address small, medium or large entities.
For the sound of dog I actually normally just use a kind of heavy-duty gloves I've epoxy-glued paper-clips on. I was gonna try other things as well when it was still just gaffed on, like pieces of horn and different types of wood, but truth be told I found this configuration to be absolutely spot-on for what I needed instantly!
For the sense of weight, I've used different stuff depending on the character it's intended for, but low-passed piezo-disc through a Radial PZDI gaffed to a sand punching-bag, or the same piezo on the wooden floor (it resonates, but the lowpass erases the feeling of wood when using it for other surfaces), which I bashed from different distances for different results with a canvas bag filled with sand, turned out to be the bee's knees for several kinds of creatures, like a werewolf-esque monster, and huge dogs. I've also used said sand-bag to slam into the floor to simulate heavy steps, but do mind the back, these things wight like a small mountain...