When I try to use standalone Izotope Rx with Pro Tools 10 with "connect" I get this error message:

The selected audio device cannot be opened. Please make sure it's not in use by another application and its drivers are up to date. (Output MMRESULT=0x20 [0x7])

Also this message is logical to me because, while in Pro Tools I can't use any other audio source, so... it would be helpful to solve this. I am using win 8.1, Focusrite Scarlett Solo. The drivers are up to date.

  • question, do both programs use the same audio output channels? in that case it's not possible. you can only use both at the same time if you have RX4 with Monitor in that case. Commented Feb 21, 2015 at 17:45
  • How to know if they are using same audio channels? I am asking about Izotope because it pops an error msg, but it's the same with youtube or anything else, media player, whatever.
    – lakistrike
    Commented Feb 21, 2015 at 18:38
  • well does your soundcard have multiple outputs and does it provide an internal mixer that allows you to route signals to different outputs? in that case you can set osx/windows up to use different outputs for different apps. it's actually really easy. Commented Feb 22, 2015 at 11:10
  • ah i see you have a stereo card. sorry, not possible then Commented Feb 22, 2015 at 11:11

2 Answers 2


You need to set up an Aux in Pro tools with Izotope Monitor as an insert, then select Monitor as the audio device in RX

  • ah i stand corrected (i thought it was connect, but that's the other addition to v4) however 'monitor' needs rx4... it's still unknown if he has this version Commented Feb 23, 2015 at 12:10
  • Yes, I do have RX4, i will try this.
    – lakistrike
    Commented Feb 24, 2015 at 12:03

Try this will benefit you Good luck enter image description here

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