This is kind of a broad question. Sounds like this in commercials and movie trailers came from the mainstream success of EDM like Skrillex etc. I hear a lot of the bread and butter tools of aggressive synthsizers - modulating the cutoff of resonant filters, etc. I hear some "lo-fi" stuff, most obvious in the beginning, that sounds like it had a reduced sample rate and bit depth.
If you want to do modern sound design techniques like this, you generally work with powerful synthesizers - I, for example, own and use a lot of the ones from Native Instruments Komplete. Absynth and FM8 are both great. Synths like this are meant to have the power and flexibility, working with envelops and modulators, to create the complex sounds like this, and you use multiple patches to assembe the soundscape you want. I highly recommmend getting Absynth and going through the groove3 tutorials on it: http://www.groove3.com/str/Absynth-5-Explained.html
I also highly recommend doing the same with FM8. It's not some simple answers, it's a whole workflow, set of tools, and way of thinking. Generally the FX are all intergrated into the synth itself, allowing them to be modulated with the envelopes to keep each effect nestled nicely into the patch to form cohesive sound.
It techs a lot of patence and technical ability as well as musical taste and viewing things from a high-level, producer's standpoint.