USB was designed as a general purpose bus. Hence, there will always be some latency. The more devices you have connected to the bus, the more problems you will run into. I suppose the only purpose a USB large diaphragm mic would have is for one or two mics during a pod cast. I would never use such a mic in my studio.
That being said, if you plan on adding more mics to your setup, you will have problems with USB.
My general advice is to stay away from USB for audio/video/realtime application. USB works well for printers.
Whether you can do real time monitoring depends on the software/driver included with the mic. Since the mic is USB, obviously you'll be doing the no-latency monitoring via software.
If the desire to use less gear is related to cost, then there are many things you can do. You can get a small mixer and mics. You can get a multi-channel interface and mics. I don't think either be that expensive.
If you want to minimize gear because of space, or hassle, then get a multi-channel FW interface and a bunch of mics. 8 channels is quite common these days.
I've asked some questions as comments to your question. If you give more details, the answer will be clearer.