Using Soundminer v4Pro with PT10 and MBox 3 Pro here and I have no problems using rewire or going out the Core Audio driver (Both of which output through the MBox).
However, from the Help>Soundminer Help menu. A quick search for "rewire" turns up this chunk of useful info from page 16, start here. There are also a number of helpful pictures that I'm not going to bother posting because they're in the SMV4_manual.pdf that the help menu should direct you to.
The last few paragraphs in particular are possibly most important in your situation.
Pro Tools and REWIRE - The one known exception to using Coreaudio is AVID/Digidesign Pro Tools. The AVID/Digidesign hardware cannot be accessed when the Pro Tools software is running. In response to this change, Soundminer developed a Rewire based connection option. When Pro Tools is running, playback via the AVID/Digidesign hardware is only possible through Rewire as Pro Tools does not allow sharing of their hardware. Rewire is a third party connectivity platform. To use Rewire, make sure your sound control preferences is set to ‘Built-in’. Do the same in your Audio/Midi Utility application(Application/Utilities). As a final preparation, make sure your Pro Tools DAE H/W buffer is set to a size compatible with the speed of your computer – the faster the computer, the smaller you can make the buffer size (accessible in your Pro Tools playback engine menu).
Each Soundminer version has a very specific sm4rewire bundle. Do not mix them up. Soundminer will automatically install the correct smv4rewire.bundle when you first launch.
To use REWIRE connectivity, the DAW host(Pro Tools in this example) must be launched first. You must then open a track (AUX) in Pro Tools and insert the Soundminer Engine from your multi-channel RTAS instrument plug-in options.
Assign the Soundminer Left/Right outputs to your channel/Aux and route that Channel/Aux to an available hardware output(V4pro will have multi- channel options enabled via multiple plug-in instantiation).
Then launch Soundminer. If connection has been successful, you will be notified and your rewire connection automatically turned on(toggle on/off is at the bottom left of the v4 interface).
In Soundminer, the toggle on/off is now active and audio played in Soundminer will be passed through the Rewire connectivity interface and routed through the DAW’s hardware and outputs:
TROUBLESHOOTING: If your cursor does not play, this would be a good indication that your Sound system Preferences have been set to the Digidesign Core Audio driver and is conflicting with Pro Tools. While this driver works fine to route audio through Digidesign/AVID hardware when Pro Tools is not running, it becomes problematic if enabled and you try to run both Pro Tools and Soundminer. Please turns this off and set it to ‘Built-in’.
REWIRE – For reference, the rewire components are installed in this location:
~/Library/Application Support/Propellerhead Software/ReWire/SM4Rewire.bundle
** Rewire is a third party standard created by Propellerheads (makers of Reason). It requires a rewire host (Pro Tools) and a rewire slave(Soundminer). As a slave we have limited control over the connection. V4pro has multi-channel Rewire operation, linked playback and transport control(not yet enabled). V4 has basic two channel stereo rewire only. Use of Rewire for other applications is for the most part similar. Host must always be launched first and quit last. Digidesign Pro Tools installs the necessary RTAS plug-in that allows the host bundle to connect to our slave bundle. If you need to access the Rewire host bundle, go directly to Propellerheads.com(makers of Rewire).