According to [their website][1]their website, you can.
Your hardware should work with it. On the Hardware Options page they say:
Third-party audio interfaces
With Pro Tools, you get the flexibility of using the software with practically any audio interface you already have or want. For ultimate quality and performance, choose an Avid interface or bundled hardware/software solution above. Or pair Pro Tools with any other audio interface that supports any of the following drivers:
- ASIO
- Core Audio
I recommend getting the free 30 day trial and check it out to see if it will work. [1]: http://shop.avid.com/store/category.do?category=pt10-software [2]: http://avid.force.com/pkb/articles/en_US/Compatibility/en422327?popup=true