I've got a Duran Duran tribute and the band is, obviously, big synth sound heavy. Trying to fit the guitar in to the live mix has been a constant struggle. I've put notch filters on the synth channels with the Q set medium wide and centered around 1kHz but it's still getting buried. Most songs aren't mixing a variety of guitar sounds, they stick to one of clean funk, dirty clean or well overdriven.
I'm looking for mixing tips to make the guitar poke through all those pads and square wave synths that are the backbone of this type of 80's pop-rock sound.
Edit: except for the dummer we all run direct. My guitars are AxeFx, direct to FoH. Keys, obviously direct. Bass: direct. The drums are mic'ed.