My post studio is an HD2 with a 192 interface. I could do most of what I do with an LE rig but prefer the security of the HD rig. In the studio I have 2 Focusrite Trackmaster Pro units for recordings voiceovers etc.
The other reason I prefer my HD rig is when I do music recording, not having latency to battle with makes tracking so much easier. I have a Focusrite Octopre for mics when I a recording music and again I prefer the hassle of taking my HD rig with me rather than work with an LE rig.
I have an LE rig based around a MacBook Pro with an Mbox Pro and a 002R. For simple speech work I will often use the mic preamps in the 002R but if it is more complex then I will use the Octopre and go into the 002R via the optical port.
As to monitoring I use BBC LS3/5a speakers together with a small active sub to cover the low end. On the road I will either take a pair of the LS3/5a speakers or I use my Sony MDR-7509 headphones.
Regarding outboard gear I have very little now. I don't use a mixer at all now other than a Behringer line mixer as a 'soft router' on the rare occasions I need to play something into Pro Tools in real time.
When I do an ISDN session I have a template session in Pro Tools to create the appropriate clean feed and monitoring. With plug-ins and a reasonable amount of I/O there is very little need for any other outboard gear.
I hope that helps.